Do you age faster without estrogen?

Your wisdom and confidence may increase as you age, but that's not the case with many of your hormone levels. During menopause, lower estrogen levels have a big impact on the skin. A lower amount of estrogen makes you prone to thinning, sagging and wrinkles. Fortunately, you can alleviate some of the skin-related effects of aging by taking care of your specific skin care needs.

skin. Estrogen deficiency after menopause causes atrophic changes in the skin and an acceleration of skin aging. Estrogens significantly modulate skin physiology, attacking keratinocytes, fibroblasts, melanocytes, hair follicles and sebaceous glands, and improving angiogenesis, wound healing and immune response. Estrogen insufficiency decreases defenses against oxidative stress; skin becomes thinner with less collagen, less elasticity, increased wrinkles, increased dryness and reduced vascularization.

Its protective function is compromised and aging is associated with poor wound healing, hair loss, pigmentary changes and skin cancer. Osteoporosis occurs when the inside of bones becomes less dense, making them more fragile and prone to fracture. Estrogen plays an important role in preserving bone mass. Estrogen signals bone cells to stop breaking down.

Basically, yes, because they don't have estrogen and estrogens determine all the changes as they enter later stages of life. Women age twice as fast as men after menopause, that is, from the moment they lose estrogen. Hormone replacement therapy doesn't work for all women. It is a therapy that must be personalized. But it can radically change a woman's perspective and perspective on her health. Estrogen determines women's normal metabolism; it is essential for cognitive development, immune function, cardiovascular function, hyperlipidemia and vaginal atrophy.

The aging process accelerates during the menopausal years thanks to a decrease in estrogen and other reproductive hormones, which help keep the skin smooth, smooth and supple. And while you can't stop the aging process completely, you can slow it down with the right products and treatments, in addition to old-fashioned common sense. People who reach menopause before age 40 should be offered hormone replacement therapy, except on rare occasions (such as having a personal history of breast cancer at a young age).Estrogen receptors have been identified in human leukocytes, monocytes, macrophages and megakaryocytes, and there is evidence to suggest that estrogen may affect the function of inflammatory cells. Wrinkles are formed due to excess sun damage over the years, as well as to the hormonal changes typical of menopause.

However, although we have a high percentage of this conundrum in common, each individual is different and it is in these small differences that the keys to health are found. Many of these effects can be reversed by replacing estrogen, which increases epidermal hydration, elasticity and thickness of the skin, in addition to reducing skin wrinkles and increasing the content and quality of collagen and the level of vascularization. In some situations, blood tests can be misleading because a lot of hormonal fluctuations occur during the perimenopause stage. Menopause, when it occurs between the ages of 45 and 55, is considered “natural” and is a normal part of aging.

In addition, estrogen also increased the expression of TGF-beta and TGF-beta type II receptors, which may be related to the proliferation of dermal fibroblasts and the secretion of the extracellular matrix (ECM), while negatively regulating the expression of matrix metalloprotease I (MMP), which could explain the increased collagen content observed in estrogen-treated skin. Menopause is the result of a transition from full ovarian function to a total lack of ovarian estrogen biosynthesis that occurs in women around the age of 50. Talk to your provider about the risks and benefits and whether hormone therapy is an option for you based on your health history, age and other factors. We found that hormone replacement therapy (HRT) can increase collagen content by 30%, while topical estrogens improve skin elasticity by reorienting the fiber.