Yes, it suppresses ovulation (if taken early in the cycle, I think I started mine on the day of my period or soon after). Estradiol is one of the main hormones that regulate the female reproductive system. It promotes ovulation and supports implantation if the egg (ovum) is fertilized. In addition to the reproductive system, estradiol also has effects on the heart, blood vessels, bones and the brain.
Estradiol is one of the most important hormones when it comes to getting pregnant. It is essential for regulating the menstrual cycle, maintaining reproductive health, and plays an important role throughout the IVF process. Next, we spoke with the medical director of Vida Fertility Alicante, Dr. Alejandra García-Villalba, about what role estradiol plays, what symptoms and causes it produces a high level of estradiol and why it is so important in IVF. Estradiol is a hormone that belongs to the estrogen group, produced mainly in the ovaries of women and, to a lesser extent, in the adrenal glands and testicles of men.
In women, estradiol is a female sex hormone that is produced in granulosa cells of the oocyte under the influence of FSH. It is important because it plays a key role in the development of the female reproductive system and in the development of secondary sexual characteristics. Estradiol is also responsible for stimulating the growth of both the follicle and the endometrium, creating optimal conditions for embryo implantation and thus facilitating the onset of pregnancy. Low levels of estradiol may be associated with difficulties conceiving in women and, in the case of young women, may be an indication of ovulation problems, early menopause or premature ovarian failure.
Excessively high or low levels of estradiol can affect the chances of a successful procedure, so it is essential to control them. Estradiol is a key hormone that plays a fundamental role in stimulating and maturing follicles, preparing the endometrium, synchronizing oocyte development and supporting the endometrium during the luteal phase, especially in in vitro fertilization (IVF) treatments. In addition, menopausal women who receive hormone replacement therapy tend to have higher levels of estradiol compared to those who don't receive hormone replacement therapy. However, when levels are higher than usual, feminine characteristics may appear, such as the development of breast tissue (gynecomastia).
Since the enzyme responsible for the production of estradiol is found primarily in adipose tissue, excess weight can increase estradiol levels and lead to gynecomastia. In short, estradiol is not only a key indicator during treatment, but it is also essential for every stage of the process to go smoothly. The use of oral contraceptives can lower estradiol levels, since they contain synthetic hormones in doses lower than that occur naturally during the menstrual cycle. This is normal and part of its function to inhibit ovulation.
These findings reveal that hormone replacement therapy with the highest dose of Prempak-C does not inhibit ovulation and that an elevated FSH level does not always indicate the absence of ovulation. Three of these women had anovulatory cycles during hormone treatment, while 3 of the 6 who did not ovulate before hormone therapy ovulated during treatment. In this study of twenty women, neither the regularity of their pre-existing menstrual cycle nor a random concentration of FSH predicted the likelihood of subsequent ovulation while being treated with the therapy. of hormone replacement.
